دانلود گزارش کارورزی و کار آموزی

چکیده : 

Over the next 10 years, the intelligent use of data will become one of the

greatest competitive advantages a company can possess. At the same time, the loss or

mishandling of data/information is one of the bigger risks facing modern businesses. As

consumers become increasingly aware of security issues, and of the value of their

data, data/information policy is moving away from the ‘gather-with-consent’ approach

toward a model that holds the business accountable at each stage of the

process. This fundamental shift in practice will need to be reflected in the data/

information management policy of the business. Yet, many companies lack up-to-date

data/information policies and few recognize the growing influence of the European

Union on the manner of data/information handling. This installment of Business Law &

Ethics Corner seeks to assist in the development of new policy by explaining key

legislative and policy initiatives in both the United States and the European Union, and

by making data management policy recommendations

چکیده : 

The cold-adapted (ca) live attenuated influenza vaccine (LAIV) strains are manufactured in embryonated

hens’ eggs. Recently, a clonal isolate from Madin Darby Canine Kidney (MDCK) cells was derived and

characterized to assess its utility as a potential cell substrate for the manufacturing of LAIV [1]. Since

MDCK cells are a transformed continuous cell line [2], and low levels of residual cellular components

(DNA and protein) are found in the intermediates and final filled vaccine, we sought to characterize the

uptake and clearance of MDCK DNA from tissues in order to assess theoretical risks associated with

manufacturing LAIV in MDCK cell culture.

In order to address this concern, MDCK DNA uptake and clearance studies were performed in Sprague

Dawley rats. DNA extracted from MDCK Master Cell Bank (MCB) cells was administered via an intranasal

(IN) or intramuscular (IM) route. Tissue distribution and clearance of MDCK DNA were then examined in

fourteen selected tissue types at selected time points post-administration using a quantitative PCR assay

specific for canine (SINE) DNA.

Results from these studies demonstrate that the uptake and clearance of MDCK DNA from tissues vary

depending on the route of administration. When DNA was administered intranasally, as compared to

intramuscularly, detectable DNA levels were lower at all time points. Thus, the intranasal route of vaccine

administration appears to reduce potential risk associated with residual host cell DNA that may be

present in cell culture produced final vaccine products.

چکیده : 

This paper deals with the problem of extracting qualitative and quantitative information

from few tomographic projections of an object without reconstructing this object. It

focuses on the extraction of quantitative information, precisely the border perimeter

estimation for a convex set from horizontal and vertical projections. In the case of a multiple

reconstruction, lower and upper bounds for the perimeter are established. In the case of

a unique reconstruction, we give conditions and a method for constructing an inscribed

polygon in a convex set only from the convex-set projections. An inequality on border

perimeter is proved when a convex set is included in another one. The convergence of

the polygon perimeter, when the number of vertices increases, is established for such

polygons.

چکیده : 

Based on the orbital resonance model, we study the two-dimensional phase plane structure of the motion of space debris orbiting the

geosynchronous ring under the combined effects of the tesseral harmonics J22, J31 and J33 of the Earth’s gravitational field. We present

the main characteristic parameters of the two-dimensional phase plane structure. We also analyze the stability of the two-dimensional

phase plane structure with numerical method. Our main findings indicate that the combined effects of the tesseral harmonics J22, J31 and

J33 fully determine the two-dimensional phase plane structure of the space debris, and it remains robust under the effect of the Earth’s

actual gravitational field, the luni-solar perturbations and the solar radiation pressure with the normal area-to-mass ratios.

چکیده : 

Space-based optical sensors for space situational awareness allow for tracking of objects that are smaller than currently capable with

ground-based systems with less influence of atmospheric phenomena. Multiple measurements must be combined in order to obtain a full

state description, but their association is uncertain a priori. In this paper, the direct Bayesian admissible region method is applied to

space-based observations. Simulation results for both a low-Earth (LEO) and geosynchronous orbit (GEO) observer are shown. For

the former, the proposed method successfully associates 101 observations of 8 Earth-orbiting objects taken over the span of 48 h.

For the latter, lack of relative motion is identified as a key difficulty in the association process. This problem can be remediated by

improved observation strategies.

چکیده : 

In this paper we present results for the global elastic parameters: Love number h2 and Shida number l2 derived from the analysis of

Satellite Laser Ranging (SLR) data. SLR data for the two low satellites STELLA ( km) and STARLETTE ( km)

observed during 2.5 years from January 3, 2005 until July 1, 2007 with 18 globally distributed ground stations were analyzed. The analysis

was done separately for the two satellites. We do a sequential analysis and study the stability and convergence of the estimates as a

function of length of the data set used.

The final adjusted values for h2 equal to 0.6163 ± 0.0037 and 0.6048 ± 0.0025, and those for l2 equal to 0.0176 ± 0.0017 and

0.1151 ± 0.0010 for STELLA and STARLETTE tracking data are compared to estimates we previously published based on data for

two high satellites LAGEOS1 ( km) and LAGEOS2 ( km) (Rutkowska and Jagoda, 2010a). A major discrepancy

between the two solutions was found for the Shida number l2.

چکیده : 

It is the primary task for a bioregenerative life support system (BLSS) to maintain the stable concentrations of CO2 and O2. However,

these concentrations could fluctuate based on various factors, such as the imbalance between respiration/assimilation quotients of the heterotrophic

and autotrophic components. They can even be out of balance through catastrophic failure of higher plants in the emergency

conditions. In this study, the feasibility of using unicellular Chlorella vulgaris of typically rapid growth as both “compensatory system” and

“regulator” to control the balance of CO2 and O2 was analyzed in a closed ecosystem. For this purpose, a small closed ecosystem called

integrative experimental system (IES) was established in our laboratory where we have been conducting multi-biological life support system

experiments (MLSSE). The IES consists of a closed integrative cultivating system (CICS) and a plate photo-bioreactor. Four volunteers

participated in the study for gas exchange by periodical breathing through a tube connected with the CICS. The plate photo-bioreactor was

used to cultivateC. vulgaris. Results showed that the culture ofC. vulgaris could be used in a situation of catastrophic failure of higher plant

under the emergencies. And the productivity could recover itself to the original state in 3 to 5 days to protect the system till the higher plant

was renewed. Besides, C. vulgaris could grow well and the productivity could be affected by the light intensity which could help to keep the

balance of CO2 and O2 in the IES efficiently. Thus, C. vulgaris could be included in the design of a BLSS as a “compensatory system” in the

emergency contingency and a “regulator” during the normal maintenance.

چکیده : 

Using Irkutsk digisonde data obtained in 2003–2011, a morphological analysis of the G condition occurrence has been made. The G

condition was found to occur during daylight hours in summer; in winter, it is extremely rare, and its appearance is associated with

intense magnetic storms. In the years of moderate solar activity, the G condition is most frequently registered at KpP4, in the forenoon.

During low solar activity, it can be observed under quiet geomagnetic conditions; in most cases, local time of its appearance shifts to

afternoon hours. The highest percentage of the G condition occurrence (7.7–6.4%) was recorded in June and July 2008 when the levels

of solar and geomagnetic activity were abnormally low.