دانلود گزارش کارورزی و کار آموزی

چکیده : 

In the past decade, in vitro transcription/translation

technologies have emerged as discovery tools for screening

large protein expression libraries, for the selection of

engineered polypeptide libraries, and as alternatives to

conventional heterologous expression for protein production.

Therapeutic proteins and peptides discovered using ribosomebased

display methods that link genetic information to the

encoded polypeptide generated by cell-free extracts, or

purified translation components, are beginning to move

forward into human clinical trials. This review details the

significant progress in in vitro translation for novel protein and

non-natural amino acid containing peptide discovery

platforms, as well as advances in the clinical-scale

production of therapeutic proteins using cell-free transcription/

translation